Northwest Arkansas Clinical Trials Center has been a dedicated dermatology research center for more than 7 years. The research center is located in the heart of Northwest Arkansas, home to a regional population of more than 500,000 residents and two large college campuses. The clinical trials center has over 1500 square feet solely dedicated to dermatology research and research subjects. The center includes a reception area, examination rooms, laboratory, locked and temperature monitored investigational product ambient storage, study coordinator offices, and temperature monitored refrigerator and -20 C freezer. All equipment undergoes certification annually.

The combined clinical trial team experience in phase I-phase IV studies exceeds 50 years. Investigational product formulation experience includes oral, intravenous, topical and other parenteral routes. All personnel have certified GCP training and most are IATA certified. The staff is very familiar with the variety of electronic data capture (EDC) platforms and are very proficient in data entry.

The center and personnel have clinical trial experience in the following dermatologic conditions in pediatric, adolescent and adult populations:

  • Atopic Dermatitis
  • Alopecia
  • Hyperhidrosis
  • Psoriasis
  • Acne
  • Common Warts
  • Seborrheic Keratosis
  • Rosacea
  • Hidradenitis suppurativa

Dermatofibrosarcoma protuberans (DFSP): Overview

What is dermatofibrosarcoma protuberans?

  Dermatofibrosarcoma_-protuberans_landing.jpg
Dermatofibrosarcoma protuberans: This raised, reddish-brown patch began as a small red lump that grew slowly.

Dermatofibrosarcoma (dur-mah-toe-fy-bro-sar-co-ma) protuberans (pro-to-bur-anz) (DFSP) is a rare skin cancer. It begins in the middle layer of skin, the dermis. DFSP tends to grow slowly. It seldom spreads to other parts of the body.

Because DFSP rarely spreads, this cancer has a high survival rate. Treatment is important, though. Without treatment, DFSP can grow deep into the fat, muscle, and even bone. If this happens, treatment can be difficult.

The first sign of this skin cancer is often a small bump on the skin. It may resemble a deep-seated pimple or rough patch of skin. DFSP can also look like a scar. In children, it may remind you of a birthmark.


Image used with permission of Journal of the American Academy of Dermatology: J Am Acad Dermatol 2005;53:76-83

 


References:
Bichakjian CK, Alam M, Andersen J et al. “Dermatofibrosarcoma protuberans: Clinical practice guidelines in oncology.” National Comprehensive Cancer Network. Version 2.2013.
Buck DW, Kim JY, Alam M, “Multidisciplinary approach to the management of dermatofibrosarcoma protuberans. J Am Acad Dermatol. 2012;67(5):861-6.
Criscione VD, Weinstock MA. “Descriptive epidemiology of dermatofibrosarcoma protuberans in the United States, 1973 to 2002.” J Am Acad Dermatol. 2007;56(6):968-73.
Halpern M, Chen E, Ratner D. “Sarcomas.” In Nouri K. [editor]. Skin Cancer. United States. McGraw Hill Medical; 2008. p. 217-18.
Irarrazaval I, Redondo P. “Three-dimensional histology for dermatofibrosarcoma protuberans: case series and surgical technique.” J Am Acad Dermatol. 2012 Nov;67(5):991-6.
Kurlander DE, Martires KJ, Chen Y et al. “Risk of subsequent primary malignancies after dermatofibrosarcoma protuberans diagnosis: a national study.” J Am Acad Dermatol 2013;68(5):790-6.
Thornton SL, Reid J, Papay FA, et al. “Childhood dermatofibrosarcoma protuberans: Role of preoperative imaging.” J Am Acad Dermatol 2005;53:76-83.


© American Academy of Dermatology. All rights reserved. Reproduction or republication strictly prohibited without prior written permission. Use of these materials is subject to the legal notice and terms of use located at https://www.aad.org/about/legal


Contact Us

Northwest AR Clinical Trials Center, PLLC

(479) 876-8205
500 S 52nd St Rogers, AR 72758-8600