Northwest Arkansas Clinical Trials Center has been a dedicated dermatology research center for more than 7 years. The research center is located in the heart of Northwest Arkansas, home to a regional population of more than 500,000 residents and two large college campuses. The clinical trials center has over 1500 square feet solely dedicated to dermatology research and research subjects. The center includes a reception area, examination rooms, laboratory, locked and temperature monitored investigational product ambient storage, study coordinator offices, and temperature monitored refrigerator and -20 C freezer. All equipment undergoes certification annually.

The combined clinical trial team experience in phase I-phase IV studies exceeds 50 years. Investigational product formulation experience includes oral, intravenous, topical and other parenteral routes. All personnel have certified GCP training and most are IATA certified. The staff is very familiar with the variety of electronic data capture (EDC) platforms and are very proficient in data entry.

The center and personnel have clinical trial experience in the following dermatologic conditions in pediatric, adolescent and adult populations:

  • Atopic Dermatitis
  • Alopecia
  • Hyperhidrosis
  • Psoriasis
  • Acne
  • Common Warts
  • Seborrheic Keratosis
  • Rosacea
  • Hidradenitis suppurativa
  Merkel-cell-carcinoma_landing.jpg
Merkel cell carcinoma: This rare skin cancer can appear on the skin as a hard patch (1) or firm bump (2).

Merkel cell carcinoma: Overview

What is Merkel cell carcinoma?

Merkel cell carcinoma (MCC) is a rare skin cancer. It is also an aggressive skin cancer. MCC is considered aggressive because it can:
  • Grow quickly and spread.
  • Return after treatment.

 

Because MCC is aggressive, doctors recommend prompt treatment. The sooner this skin cancer is treated the better the outcome. To improve a patient’s outcome, a team of doctors usually creates the treatment plan for MCC. This approach allows the patient to benefit from the expertise of specialists in different areas of medicine. The team often includes a dermatologist, a medical oncologist (cancer specialist), and a radiation oncologist (specialist in treating cancer with radiation.) Other doctors may also be a part of this team.

It is important for patients diagnosed with MCC to:

  • Keep all appointments with their doctors.
  • Check their skin and lymph nodes for signs of cancer as recommended.

 

These actions help find cancer as early as possible.


Images used with permission of Journal of the American Academy of Dermatology: J Am Acad Dermatol. 2012; 66:923-7

 


References:
Harting MS, Ludgate MW, Fullen DR et al. “Dermatoscopic vascular patterns in cutaneous Merkel cell carcinoma,” J Am Acad Dermatol 2012; 66(6): pages 923-7.
Heath M, Jaimes N, Lemos BD et al. “Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.” J Am Acad Dermatol 2008; 58:375-81.
Lemos BD, Storer BE, Iyer JG et al. “Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system.” J Am Acad Dermatol 2010; 63:751-61.
Nghiem P, Jaimes N. “Merkel Cell Carcinoma.” In: Wolff K, Goldsmith LA, Katz SI, et al. editors. Fitzpatrick’s Dermatology in General Medicine, 7th ed. United States of America, McGraw Hill Medical; 2008. p. 1087-94.


© American Academy of Dermatology. All rights reserved. Reproduction or republication strictly prohibited without prior written permission. Use of these materials is subject to the legal notice and terms of use located at https://www.aad.org/about/legal


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Northwest AR Clinical Trials Center, PLLC

(479) 876-8205
500 S 52nd St Rogers, AR 72758-8600