Northwest Arkansas Clinical Trials Center has been a dedicated dermatology research center for more than 7 years. The research center is located in the heart of Northwest Arkansas, home to a regional population of more than 500,000 residents and two large college campuses. The clinical trials center has over 1500 square feet solely dedicated to dermatology research and research subjects. The center includes a reception area, examination rooms, laboratory, locked and temperature monitored investigational product ambient storage, study coordinator offices, and temperature monitored refrigerator and -20 C freezer. All equipment undergoes certification annually.

The combined clinical trial team experience in phase I-phase IV studies exceeds 50 years. Investigational product formulation experience includes oral, intravenous, topical and other parenteral routes. All personnel have certified GCP training and most are IATA certified. The staff is very familiar with the variety of electronic data capture (EDC) platforms and are very proficient in data entry.

The center and personnel have clinical trial experience in the following dermatologic conditions in pediatric, adolescent and adult populations:

  • Atopic Dermatitis
  • Alopecia
  • Hyperhidrosis
  • Psoriasis
  • Acne
  • Common Warts
  • Seborrheic Keratosis
  • Rosacea
  • Hidradenitis suppurativa
  sebaceous_carcinoma_landing.jpg
Sebaceous cell carcinoma: The growth on this man’s lower eyelid is sebaceous carcinoma.

Sebaceous carcinoma: Overview

Also called sebaceous gland carcinoma, sebaceous gland adenocarcinoma, or meibomian gland carcinoma.

What is sebaceous carcinoma?

Sebaceous (suh-bey-shuhs) carcinoma (SC) is a rare skin cancer. It is considered an aggressive skin cancer because it can spread.

Found early and treated, treatment is often successful. It is helpful to know that:

  • Most SCs begin on an eyelid.
  • You may notice a painless, round, firmly implanted tumor on your upper or lower eyelid.
  • Sometimes you have to pull gently on your eyelid to see the tumor.

 

This cancer may begin elsewhere. It can develop in any sebaceous gland. We have sebaceous glands on most areas of our skin. SC tends to develop in and around the eyes because we have the greatest number of sebaceous glands in that area.

When this cancer begins in an eyelid, a dermatologist may refer to it as a meibomian (my-BOW-me-en) gland carcinoma. This is a unique type of sebaceous gland found in the eyelids.

Other growths develop on and around the eyelids. Most growths are benign (not cancer). If you notice a growth on your eyelid that remains despite treatment, you should make an appointment to see a dermatologist. The sooner this cancer is diagnosed and treated the better the outcome. If SC spreads, it can be deadly.


Image used with permission of the Journal of the American Academy of Dermatology: J Am Acad Dermatolog 1995: 33: 1-15.


 

References:
Martinelli PT, Cohen PR, Schulze KE et al. “Sebaceous Carcinoma.” In Nouri K. [editor]. Skin Cancer. United States. McGraw Hill Medical; 2008. p. 240-9.
Nelson BR, Hamlet KR, Gillard M et al. “Sebaceous carcinoma.” J Am Acad Dermatol 1995; 33: 1-15; quiz 6-8.
Spencer JM, Nossa R, Tse DT et al. “Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery.” J Am Acad Dermatol 2001;44:1004-9.


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Northwest AR Clinical Trials Center, PLLC

(479) 876-8049
500 S 52nd St Rogers, AR 72758-8600