Northwest Arkansas Clinical Trials Center has been a dedicated dermatology research center for more than 7 years. The research center is located in the heart of Northwest Arkansas, home to a regional population of more than 500,000 residents and two large college campuses. The clinical trials center has over 1500 square feet solely dedicated to dermatology research and research subjects. The center includes a reception area, examination rooms, laboratory, locked and temperature monitored investigational product ambient storage, study coordinator offices, and temperature monitored refrigerator and -20 C freezer. All equipment undergoes certification annually.
The combined clinical trial team experience in phase I-phase IV studies exceeds 50 years. Investigational product formulation experience includes oral, intravenous, topical and other parenteral routes. All personnel have certified GCP training and most are IATA certified. The staff is very familiar with the variety of electronic data capture (EDC) platforms and are very proficient in data entry.
The center and personnel have clinical trial experience in the following dermatologic conditions in pediatric, adolescent and adult populations:
- Atopic Dermatitis
- Common Warts
- Seborrheic Keratosis
- Hidradenitis suppurativa
Stasis dermatitis: Overview
Also called gravitational dermatitis, venous eczema, and venous stasis dermatitis
This condition develops in people who have poor circulation. Because poor blood flow usually occurs in the lower legs, this is where stasis dermatitis often develops. It may occur in one or both legs. Stasis dermatitis can develop in other areas, but this is rare.
Stasis dermatitis is most common in the lower legs because leg veins have one-way valves, which play an important role in circulating our blood. These valves push blood up the legs. As we age, these valves can weaken and stop working properly. Some blood can leak out and pool in the legs. Your dermatologist may refer to this as “venous (vee-nis) insufficiency.”
If you’ve been diagnosed with venous insufficiency, it does not mean that you will get stasis dermatitis. Watching for signs and symptoms of stasis dermatitis is important though. Treatment and self-care can prevent the stasis dermatitis from becoming severe.
Swelling around the ankle is often the first sign of stasis dermatitis. The swelling tends to clear while you sleep — and return during the day. Other early signs are discolored skin and varicose veins.
Image used with permission of the American Academy of Dermatology National Library of Dermatologic Teaching Slides.
Flugman, SL et al. (authors) and Elston DM et al (editors). “Stasis dermatitis.” Medscape. Last updated July 2014.
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Weaver J, Billings SD. “Initial presentation of stasis dermatitis mimicking solitary lesions: A previously unrecognized clinical scenario.” J Am Acad Dermatol. 2009 Dec;61(6):1028-32.
Trayes KP, Studdiford JS, et. al. “Edema: Diagnosis and management.” Am Fam Physician. 2013 Jul 15;88(2):102-10.